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HPV (Human Papillomavirus) Vaccine

Vaccines to Prevent HPV

Vaccine Basics

HPV vaccines are available for females and males to protect against the types of HPV (human papillomavirus) that most commonly cause health problems such as HPV-related cancers and disease.

HPV vaccine is important because it is an anti-cancer vaccine. Both of the HPV vaccines, Cervarix and Gardasil, can prevent most cases of cervical cancer in females, if given before a person is exposed to the virus. One HPV vaccine, Gardasil, can prevent many cases of anal cancer, as well as most genital warts in both females and males. Protection from HPV vaccine is expected to be long-lasting. The best way a person can be sure to get the most benefit from HPV vaccination is to complete all three doses before beginning sexual activity.  Women should still get regular Pap tests: HPV vaccination is not a substitute for cervical cancer screening.


Two HPV vaccines have been used in the U.S. and around the world for several years. These vaccines have been studied carefully and shown to be very safe. Learn more about possible side effects of HPV vaccines.


HPV vaccine is given as a three-dose series:

1st Dose


2nd Dose

1 to 2 months after Dose 1

3rd Dose

6 months after Dose 1


For Girls and Women

Two vaccines (Cervarix and Gardasil) are available to protect females against the types of HPV that cause most cervical cancers. One of these vaccines (Gardasil) also protects against most genital warts. Gardasil has also been tested and shown to protect against cancers of the vagina, vulva and anus.

Both vaccines are recommended for 11- and 12-year-old girls, and for women 13 through 26 years old who did not get any or all of the three recommended doses when they were younger. These vaccines can also be given to girls beginning at age nine. It is recommended that females get the same vaccine brand for all three doses, whenever possible.

HPV vaccine is not recommended for pregnant women. However, receiving HPV vaccine when pregnant is not a reason to consider terminating the pregnancy. Women who are breast feeding may get the vaccine.

For Boys and Men

One vaccine (Gardasil) protects males against most genital warts and anal cancers. This vaccine is recommended for 11- and 12-year-old boys, and for men 13 through 21 years old who did not get any or all of the three recommended doses when they were younger . It may be given to men aged 22-26 years who haven’t completed the 3-dose series. This vaccine can also be given to boys beginning at age nine. The vaccine is also recommended for gay and bisexual men (or any man who has sex with a man), as well as for men with compromised immune systems (including people living with HIV/AIDS) through age 26, if they did not get fully vaccinated when they were younger.

The best way a person can be sure to get the most benefit from HPV vaccination is to complete all three doses before beginning sexual activity.

Learn more about HPV and vaccines to prevent cervical cancer by reading answers to frequently asked questions.

About HPV

What is HPV (Human Papillomavirus)?

Genital human papillomavirus (also called HPV) is the most common sexually transmitted infection. There are more than 40 HPV types that can infect the genital areas of males and females. These HPV types can also infect the mouth and throat. Most people who become infected with HPV do not even know they have it. HPV is not the same as herpes or HIV (the virus that causes AIDS). These are all viruses that can be passed on during sex, but they cause different symptoms and health problems.

HPV can cause cervical cancer in women. HPV is also associated with several less common cancers, such as vaginal and vulvar cancers in women and other types of cancer in both men and women. It can also cause genital warts and warts in the throat.

A person can have HPV even if years have passed since he or she had sexual contact with an infected person. Most infected persons do not realize they are infected or that they are passing the virus on to a sex partner. It is also possible to get more than one type of HPV.

Who gets HPV?

Almost all men and women who are sexually active will get at least one type of HPV at some point in their lives; however, most will never know that they have gotten an HPV infection. HPV is passed on through genital contact, most often during vaginal and anal sex. HPV may also be passed on during oral sex and genital-to-genital contact. HPV can be passed on between straight and same-sex partners—even when the infected partner has no signs or symptoms.

Very rarely, a pregnant woman with genital HPV can pass HPV to her baby during delivery. In these cases, the child can develop warts in the throat, a condition called Juvenile-Onset Recurrent Respiratory Papillomatosis (JORRP).

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